Exploring a genetic basis for the metabolic perturbations in ME/CFS using UK Biobank
A large genetic study reveals disrupted links between genes and metabolism in ME/CFS, highlighting altered lipid and cortisol pathways that may explain the condition’s metabolic and biological diversity.
OMF Directors Interview
We’re excited to share an interview with all of OMF’s Directors. This panel discussion focuses on the big picture and draws connections across OMF’s research portfolio. An Interview with OMF’s Directors Watch Now Click here to read the video transcript. The Heart of the Matter In an interview with Dr. Danielle Meadows, all of OMF’s […]
An Interview with Chris Armstrong, PhD, and Wenzhong Xiao, PhD
In today’s interview, Dr. Chris Armstrong and Dr. Wenzhong Xiao, two of OMF’s Directors, talk about what they think is going on in ME/CFS, including differences in producing energy and the immune and central nervous systems being out of balance. They also discuss connections between their research. Remember — from 1 November to 2 December, […]
An Interview with Chris Armstrong, PhD, and Wenzhong Xiao, PhD: Transcript
An Interview with Chris Armstrong, PhD, and Wenzhong Xiao, PhD: Transcript Dr. Meadows: Hi everyone and thank you for listening to our interview today. I am Dr. Danielle Meadows, OMF’s VP of Research Programs and Operations, and I’m joined today by Dr. Chris Armstrong, the Director of our Melbourne ME/CFS Collaboration, and Dr. Wenzhong Xiao, the […]
Partnering for Impact: OMF Australia x Care Mobile
OMF Australia has partnered with Care Mobile to turn everyday connectivity into impact. Get 20% off your plan, enjoy double data, and help fund life-changing research into ME/CFS, Long COVID, and related diseases—simply by choosing OMF Australia as your charity.
Steroid Dynamics in ME/CFS: New Publication
Today, we are pleased to share a new publication, Steroid Dynamics in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome: A Case-Control Study using Ultra Performance Supercritical Fluid Chromatography Tandem Mass Spectrometry. The Heart of the Matter OMF’s research centres in Melbourne and Uppsala published a study of steroid hormones—molecules that control a lot of important systems in the […]
How common is ME/CFS — and how has that changed?
ME/CFS (myalgic encephalomyelitis/chronic fatigue syndrome) now affects an estimated 275 million people worldwide—a dramatic increase driven by the COVID-19 pandemic and Long COVID. In Australia, over 945,000 people are living with ME/CFS, and in New Zealand, 185,000. This widespread, often disabling condition highlights the urgent need for greater awareness, research, and support.
SIMPLE Study: Impact of Saline Infusion on ME/CFS, POTS and Long COVID
The study aims to compare the effectiveness of different saline formulations, including a placebo, in individuals with ME/CFS, Long COVID, and POTS, to determine the most beneficial types and understand their impact on patient improvement.
Blood flow, neuroinflammation, and metabolism in ME/CFS
The study aims to explore the structural, neuro-vascular, and biochemical differences in the brains of individuals with ME/CFS, Long COVID, and POTS to elucidate the underlying pathology and identify potential targets for effective treatment strategies.
Personalised Treatment Trials
The study aims to deeply characterise patients before, during and after treatments are trialled through their GP. Producing large scale data in combination with treatment outcome will be used to produce a predictive algorithm to improve the connection of patients to appropriate treatment options sooner.