The study will explore the structural, neuro-vascular, and biochemical differences in the brains of individuals with ME/CFS, Long COVID, and POTS to elucidate the underlying pathology and identify potential targets for effective treatment strategies.
Emerging evidence suggests a potential link between ME/CFS and Long COVID, characterised by similar symptomatology. Additionally, POTS frequently co-occurs with ME/CFS and LC, further complicating symptom management and reducing patients’ quality of life.
Neuroinflammation has recently gained attention as a potential mechanism underlying ME/CFS and LC, with proposed pathways involving sustained glial activation and hypothalamic neuroinflammation. Glutamate dysregulation in the central nervous system, possibly exacerbated by neuroinflammation, may contribute to neuroendocrine dysfunction observed in ME/CFS and LC. Furthermore, reduced brain blood flow could be central to all 3 conditions.
This study aims to investigate brain structural, neuro-vascular, and biochemical differences between groups to deepen our understanding of ME/CFS, LC and POTS pathology and develop effective treatments. By examining astrocyte activity, metabolic variations, cerebral blood flow responses to exercise, and neuroinflammatory markers, we seek to uncover key mechanisms driving ME/CFS symptoms and identify potential therapeutic targets.
Open Medicine Foundation Australia Limited is registered as a charity with the Australian Charities and Not-for-profits Commission (ACNC). We are authorised by the Australian Tax Office as a deductible gift recipient (DGR). Donations of $2 or more are tax-deductible.
ABN 81 635 273 415
Open Medicine Foundation Australia Limited
C/O Accru Melbourne Pty Ltd
50 Camberwell Road
Hawthorn East VIC 3124
OMF Australia acknowledges the Traditional Custodians of the lands on which we operate, the Aboriginal and Torres Strait Islander peoples. We extend our respect to Elders past and present, recognising their enduring connection to country, knowledge, and stories.
Make the most of your donation by donating your Bitcoin, Ethereum, and other cryptocurrencies directly to OMF Australia rather than selling and donating the after-tax proceeds.
OMF Australia can accept cryptocurrency donations of any amount.
Donating cryptocurrency is a non-taxable event, meaning you do not owe capital gains tax on the appreciated amount and can deduct it on your taxes. This makes Bitcoin and other cryptocurrency donations one of the most tax-efficient ways to support your favorite cause. If you want to learn more about how donating crypto can lower your taxes, check out thegivingblock.com/faq.
Talk to a crypto-savvy tax professional or connect with The Giving Block to get connected with one.
We accept the following cryptocurrencies: Bitcoin (BTC), Ether (ETH), Litecoin (LTC), Bitcoin Cash (BCH), Zcash (ZEC), Gemini Dollar (GUSD), Basic Attention Token (BAT), Chainlink (LINK), 0x (ZRX), Storj (STORJ), Dai (DAI), Amp (AMP), The Graph (GRT), UMA (UMA), 1inch (1INCH).
