Studying CSF to further reveal pathogenesis mechanisms in ME/CFS

The goal of this research is to reveal more information about the role of immunology and neuroinflammation in ME/CFS, and the underlying mechanisms of related pathogenesis that takes place.
Multi-Omic Approaches to Solve Post-Acute COVID-19 (MOSAIC)

The purpose of this study is to facilitate early detection of ME/CFS in people with Long COVID and better understand disease progression.
Life Improvement Trial (LIFT) has officially begun!

The Life Improvement Trial (LIFT) has officially begun! Conducting a proper clinical trial and ensuring all logistics are set up takes time, so we are excited to share that Open Medicine Foundation’s Life Improvement Trial (LIFT) has officially launched. Recruitment and screening began in August and the first participants have now been enrolled. What is […]
Major Milestone: Australian Government Funds Update of ME/CFS & Long COVID Clinical Guidelines

We are thrilled to announce that, as a direct outcome of the Canberra Roundtable convened in late March and led by Emerge Australia with the support of Open Medicine Foundation Australia, the Australian government has committed funding to update the clinical guidelines for ME/CFS and Long COVID. The current clinical guidelines for ME/CFS are over […]
Video Update: Personalised Treatment Trials

The Heart of the Matter General practitioners (GPs) often trial different treatments with their ME/CFS and Long COVID patients. In partnership with GPs, by studying the outcomes of each treatment, the patient’s lived experience, and the personal history of the patient, the Personalised Treatment Trials project is looking to understand why someone may or may […]
Video Update: Food and Saline Infusions in ME/CFS Research

The Heart of the Matter Food and saline infusions are both known to have an impact on ME/CFS symptoms. The Melbourne ME/CFS Collaboration is aiming to identify responses to different foods using objective measures, which may also prove useful in future trials. The team will also try to understand the impact of saline infusions to […]
Video Update: MELLOW Study Explores Hormonal Fluctuations in ME/CFS and Long COVID

The Heart of the Matter Hormones impact the immune system and energy metabolism, which are both considered major parts of the biological cause of ME/CFS. Changes in hormone levels may impact the development of the disease and its severity. The MELLOW project aims to measure fluctuations in hormones across the menstrual cycle, and identify how […]
Recommendation 8 of the Long COVID Inquiry

On 27 March, at Parliament House in Canberra, Emerge Australia, with the support of Open Medicine Foundation Australia, convened a meeting of clinical, scientific and patient representatives. The agenda centred on the critical needs of the estimated 250,000 Australians of all ages and from various regions who are living with ME/CFS. Notably, with 75% of […]
Understanding Post Exertional Malaise (PEM) in ME/CFS
Post-exertional malaise (PEM) is a defining symptom of myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS), marked by a significant worsening of symptoms or the development of flu-like symptoms following physical or mental exertion. PEM can be triggered by even minimal activity and lead to severe and prolonged debilitation. Key Characteristics of Post-Exertional Malaise PEM manifests as a […]
New Publication: Unravelling ME/CFS and Long COVID Connections by Dr. Christopher Armstrong

Today, we are excited to share a new publication from Christopher Armstrong, PhD, and colleagues: “Unravelling shared mechanisms: insights from recent ME/CFS research to illuminate long COVID pathologies.” This comprehensive review is proudly supported by OMF Australia. From the Desk of Christopher Armstrong, PhD, Director of the Melbourne ME/CFS Collaboration I am proud to present […]